Anti-Aging Ultra Cream

Overview of Anti-Aging Ultra Cream

Dosage Strength of Anti-Aging Ultra Cream

Ascorbic Acid / Azelaic Acid / Alpha Lipoic Acid / DMAE / Aloe Vera / Estriol / Progesterone 10/5/1/4/0.5/0.1/2% 30 mL Pump

General Information

As we grow older our skin will lose its ability to effectively repair the visible signs of age. As skin loses its youthful levels of firmness and elasticity, facial contours may become less defined even as wrinkles become increasingly pronounced.

Face Renewal Cream is a mixture of scientifically backed, effective ingredients that may help to mitigate the effects of age on skin for a more youthful complexion.

Face Renewal Cream accomplishes this with seven substances:

  • Ascorbic Acid
  • Azelaic Acid
  • Alpha Lipoic Acid
  • DMAE
  • Aloe Vera
  • Estriol
  • Progesterone

This combination of ingredients may act to not only improve the surface appearance of facial skin but also may stimulate collagen production beneath the skin to minimize the appearance of fine lines and wrinkles and give the face a smoother, more refreshed appearance.

Why is collagen health so important? Collagen is a vital fibrous protein primarily found in connective tissues as well as:

  • In The Bones
  • In The Joints
  • A Major Component of Skin

Making up around 30% of all the body’s proteins, collagen is also the most abundant protein in the human body. The word collagen comes from the ancient Greek word kolla; which means glue.

The function of collagen is to hold the body together, while also providing firmness and strength. Type 1 collagen fibrils are so strong in fact, that - gram for gram - they’re stronger than steel.

The aging of skin, which is seen in the form of lines, wrinkles and pigment changes occurs due to the breakdown of collagen. This occurs naturally with age, but also with damage from exposure to the sun1 or disease.2

The ingredients in Face Renewal Cream may help to strengthen collagen while smoothing skin for a more youthful appearance.

Azelaic Acid: Azelaic acid is a chemical not only commonly found in various grains, but is also naturally synthesized by the yeast that exists on healthy skin.3

Azelaic acid is a potent antioxidant with powerful anti-inflammatory and antibacterial properties that may show promising results including4

  • Brigthen Skin Tone
  • Visibly Improve Skin Texture
  • Reduce The Visibility of Blemishes

Commonly used to treat acne, research has demonstrated that azelaic acid may be used to effectively treat rosacea, flaky skin, and hyper-pigmentation.5

Azelaic acid also functions as a keratolytic, which means it may help return abnormal growths on the skin back to normal.4

Ascorbic Acid: Although vitamin C is a critical nutrient for overall health, very little reaches the skin when taken orally.6

As levels of vitamin C in skin decline with age7 replenishing levels directly in the skin may help combat collagen degradation and oxidative stress. Results from clinical trials have shown that when applied topically, vitamin C may promote collagen formation and mitigate the effects of free radicals, helping to maintain firmer and more youthful skin.

Alpha Lipoic Acid: Alpha lipoic acid (ALA) is naturally found in the mitochondria of our cells as part of an enzyme system that assists in the production of energy.8

ALA is both water and fat-soluble so that it can be easily absorbed through the lipid (fat) layers of the skin and also works as a free-radical fighter in the cell’s plasma membrane to act as a strong antioxidant.9

Used topically, ALA may offer multiple benefits to skin. ALA may cause a significant decrease in the appearance of under-eye circles, loss of firmness, and puffiness.10

ALA’s anti-inflammatory effect may also help reduce visible blotchiness and redness, potentially resulting in a more even skin tone. ALA may also help minimize the appearance of pores and produce a healthier glow to skin.11

ALA may also be an effective solution to help minimize visible fine lines and wrinkles because of its capacity to regulate the production of nitric oxide, which influences blood flow to the skin.12

DMAE: DMAE is the abbreviation for an antioxidant membrane stabilizer called dimethylaminoethanol.

DMAE can be applied directly to the skin and may help tighten skin and reduce the appearance of sagging, as well as help improve firmness and elasticity while smoothing lines and wrinkles.13

DMAE may enhance the effects of other antioxidants and is frequently used in combination with Vitamins A, E, C or alpha lipoic acid.14

Aloe Vera: Aloe vera is a cactus plant belonging to the Liliaceae family. It is native to dry climates like those found in parts of Africa and India, and has been used for centuries in traditional medicine.

Aloe vera contains two hormones: Auxin and Gibberellins. These two hormones have wound healing and anti-inflammatory properties that may improve the appearance of skin. 15The Gibberellins in aloe vera may also stimulate the growth of new cells. Aloe vera may be used to encourage skin to heal with minimal scarring.15

Estriol: One of the many roles of estrogen in the body is to increase the synthesis of collagen,16 which is the skin’s underlying support structure. Collagen also promotes skin thickness and elasticity. The skin is an important estrogen-responsive endocrine tissue. Without the growth-promoting effects of estrogen, skin may wither away.

Estriol is a “weak” estrogen, which can be synthesized from plant sources. Estriol doesn’t need to be counterbalanced by progesterone and may not have a widespread effect on the body. This makes estriol an ideal estrogen for topical use since research suggests its application remains primarily in the skin, rather than in the bloodstream.17

Progesterone: Progesterone is a hormone that occurs naturally in the body and is produced by the ovaries. It may reverse the acceleration of the skin's aging process due to menopause, helping to maintain a more youthful appearance.18

What is this medicine used for? Face Renewal Cream may restore a more youthful appearance by encouraging renewed production of healthy collagen for less visible fine lines and wrinkles and brighter skin.

Storage

Store this medication in its original container at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.

  • 1. Jariashvili, Ketevan, et al. “UV damage of collagen: insights from model collagen peptides.” Biopolymers 97.3 (2012): 189-198.
  • 2. Brickley-Parsons, D. I. A. N. E., et al. “Biochemical changes in the collagen of the palmar fascia in patients with Dupuytren’s disease.” The Journal of Bone & Joint Surgery 63.5 (1981): 787-797.
  • 3. Del Rosso, James Q. “Azelaic Acid Topical Formulations: Differentiation of 15% Gel and 15% Foam.” The Journal of Clinical and Aesthetic Dermatology 10.3 (2017): 37–40. Print.
  • 4. a. b. Fariba Iraji, Ali Sadeghinia, Zabiholah Shahmoradi, Amir Hossein Siadat, Abolfazl Jooya. Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris. Department of Dermatology, Al-Zahra Hospital.
  • 5. Cutis [01 Jan 1996, 57(1 Suppl):36-45]. Melanin hyperpigmentation of skin: melasma, topical treatment with azelaic acid, and other therapies.
  • 6. Farris PK. Topical vitamin C: a useful agent for treating photoaging and other dermatologic conditions. Dermatol Surg. 2005 Jul;31(7 Pt 2):814-7.
  • 7. Rhie G1, Shin MH, Seo JY, Choi WW, Cho KH, Kim KH, Park KC, Eun HC, Chung JH. Aging- and photoaging-dependent changes of enzymic and nonenzymic antioxidants in the epidermis and dermis of human skin in vivo. J Invest Dermatol. 2001 Nov;117(5):1212-7.
  • 8. Liu J1. The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview. Neurochem Res. 2008 Jan;33(1):194-203. Epub 2007 Jun 29.
  • 9. University of Maryland Medical Center. http://www.umm.edu/health/medical/altmed/supplement/alphalipoic-acid.
  • 10. Beitner, Harry. (2003). Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% α-lipoic acid related to photoageing of facial skin. The British journal of dermatology. 149. 841-9. 10.1046/j.1365-2133.2003.05597.x.
  • 11. Beitner, Harry. (2003). Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% α-lipoic acid related to photoageing of facial skin. The British journal of dermatology. 149. 841-9. 10.1046/j.1365-2133.2003.05597.x.
  • 12. Oregon State University. Linus Pauling Institute. http://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid.
  • 13. Grossman, Rachel. (2005). The Role of Dimethylaminoethanol in Cosmetic Dermatology. American journal of clinical dermatology. 6. 39-47. 10.2165/00128071-200506010-00005.
  • 14. Morissette, G & Germain, L & Marceau, François. (2007). The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology. The British journal of dermatology. 156. 433-9. 10.1111/j.1365-2133.2007.07681.x.
  • 15. a. b. Surjushe, Amar, Resham Vasani, and D G Saple. “ALOE VERA: A SHORT REVIEW.” Indian Journal of Dermatology 53.4 (2008): 163–166. PMC. Web. 19 Sept. 2017.
  • 16. Stevenson, Susan, and Julie Thornton. “Effect of Estrogens on Skin Aging and the Potential Role of SERMs.” Clinical Interventions in Aging 2.3 (2007): 283–297. Print.
  • 17. Schmidt JB1, Binder M, Demschik G, Bieglmayer C, Reiner A. Treatment of skin aging with topical estrogens. Int J Dermatol. 1996 Sep;35(9):669-74.
  • 18. John R. Lee, M.D. Slowing the Aging Process With Natural Progesterone. https://www.bellissimomedical.com/pdf/case-studies/women/progesterone-benefits/slowing-aging-with-progesterone.pdf

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