Niacin, a form of vitamin b3, is critical for the body’s energy metabolism.[1] Beyond potential metabolic functions, niacin may have antidyslipidemic properties, making it a potential option for the management of dyslipidemia and related cardiovascular disorders.[2]
Furthermore, niacin serves as a precursor to nicotinamide adenine dinucleotide (NAD), an essential coenzyme involved in various cellular processes, including energy production and regulation of gene expression.[1] Through conversion to the metabolically active NAD, niacin assists with the maintenance of cellular integrity and function, potentially impacting a wide range of physiological functions, from metabolism to cellular signaling and oxidative stress management.[1]
Niacin is a vasodilator, meaning it may help widen blood vessels, which in turn may assist with improving blood flow.[3] This may result in flushing, particularly in the face, neck or chest.[3][4]
Some sustained-release forms of niacin may have lower reported flushing but may have increased risk of liver toxicity compared to immediate-release forms.[4]