General Information: Lipotropic compounds are used on the potential for release of fat deposits in some parts of the body. They sometimes go by the names Lipo-Den, Lipo-Plex, Lipo Shot, or MIC Injection. The lipotropic agents included in this injection are:
- Methionine, which helps the liver maintain the optimal ability to process fatty acids;1
- Choline, which stimulates the mobilization of fatty acids and prevents their deposition in a given part of the body;2 and,
- Inositol, which aids in the transport of fat into and out of the liver and intestinal cells, acts synergistically with choline, exhibiting more lipotropic activity than when administered alone.3
Typically, these compounds are administered in concert. Injections can be administered up to twice a week. B12 is purported by its users and practitioners to help speed up overall metabolic processes and create a greater feeling of overall energy & well-being.4 Because these lipotropics are structurally and functionally closely related to the B-vitams, they are often employed together in the hope of potentiating the potential for fat-loss, thus while the MIC mixture and B vitamin(s) are often injected separately, they are part of the same overall injection cycle. The non-vitamin compounds (MIC) that are injected into the body stimulate the liver into optimizing the process of metabolism, elevate the movement of and utilization of fat, and boost the metabolic power of the body for awhile.
Other compounds are included as an attempt to further potentiate these effects:
- Thiamine HCl (vitamin B1)
- Dexpanthenol (vitamin B5)
As soon as the effect of all 6 of these substances wears out, the body gradually begins returning to its normal rate of fat and general metabolism.
Who should not take this medicine? If you have an allergy to methionine, inositol, choline, or any part of this medicine. Tell your healthcare provider if you are allergic to any medicine. This includes rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
What are the precautions when taking this medicine? You may experience injection site irritation. Be careful if you drive or do anything that requires you to be alert.
Key warnings before taking this medicine: This medication is to be injected intramuscularly.
How is it best taken? This medication is to be injected intramuscularly. DO NOT inject intravenously. This medicine can be taken at any time during the day. Follow diet plan and exercise program as recommended by health care provider.
What do I do if I miss a dose? If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Take your next regularly scheduled dose. Do not take two doses at the same time.
What are some possible side effects of this medicine? Potential side effects include stomach upset and urinary problems due to the strain the injections place on the kidneys. Depression is another possible side effect. Some patients are unable to control their urine, and/or have diarrhea. Finally, some patients reported an unpleasant odor. Lipotropic injections change the function of the digestive system temporarily. This can result in extreme exhaustion, since the body is not used to working at this level and condition. Unexplained pain in unrelated parts of the body is another potential side effect. Patients have complained of pain in the neck and parts of the hand. How these injections cause these pains is not clear. Some patients have also experienced joint pains and allergic reactions to the injections. Call your healthcare provider immediately if you are experiencing any signs of an allergic reaction: wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat; also if you experience severe behavioral problems, chest pain or pressure or fast heartbeat, severe dizziness or passing out, nervousness and excitability, or severe headache.
How should I store this medicine? Store medicine at room temperature between 68°F to 77°F (20°C - 25°C) away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the expiration date. Do not flush unused medications or pour down a sink or drain.
- 1. Best CH, Ridout JH. "The Lipotropic Action of Methionine". Journal of Physiology. 3 Oct 1939;97:489-494.
- 2. Artom C. "Mechanism of Action of Choline". American Journal of clinical Nutrition
- 3. Gavin G, Patterson J, McHenry W. " Comparison of the Lipotropic Effects of Choline, Inositol, and Lipocaic in Rats". Journal of Biochemistry. 29 Jan 1943;148:275-279.
- 4. Solomon L. "Disorders of cobalamin (Vitamin B12) metabolism: Emerging concepts in pathophysiology, diagnosis and treatment". Elsevier Review. pp. 1-15. Web.